Mucosal Changes in the Small Intestines in Portal Hypertension: First Study Using the Pillcam SB3 Capsule Endoscopy System.
- Author:
Mahesh Kumar GOENKA
1
;
Bhavik Bharat SHAH
;
Vijay Kumar RAI
;
Surabhi JAJODIA
;
Usha GOENKA
Author Information
- Publication Type:Original Article
- Keywords: Capsule endoscopy; Intestine, small; Hypertension, portal; Cirrhosis; PillCam SB3
- MeSH: Anemia; Capsule Endoscopy*; Edema; Erythema; Fibrosis; Hemorrhage; Humans; Hydrogen-Ion Concentration; Hypertension, Portal*; Intestine, Small*; Polyps; Prevalence; Telangiectasis; Varicose Veins
- From:Clinical Endoscopy 2018;51(6):563-569
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: To evaluate patients with portal hypertension (PH) of varied etiologies for portal hypertensive enteropathy (PHE) using the PillCam SB3 capsule endoscopy (CE) system. METHODS: Consecutive patients with PH presenting with unexplained anemia and/or occult gastrointestinal bleeding were evaluated using the PillCam SB3 CE system. Abnormal findings were categorized as vascular or non-vascular. The patients with ongoing bleeding caused by PHE were treated. The correlation of the CE scores of PHE with the clinical, laboratory, and endoscopic features was determined. RESULTS: Of the 43 patients included in the study, 41 (95.3%) showed PHE findings. These included varices (67.4%), red spots (60.5%), erythema (44.2%), villous edema (46.5%), telangiectasia (16.3%), and polyps (16.3%). The CE scores varied from 0 to 8 (mean±standard deviation, 4.09±1.8). Five patients (11.6%) showed evidence of ongoing or recent bleeding due to PHE. Three of these five patients underwent endotherapy, and one patient underwent radiological coil placement. CONCLUSIONS: The PillCam SB3 CE system revealed a high prevalence of PHE in the patients with PH. Using this system, evidence of bleeding due to PHE was found in a small but definite proportion of the patients.
