Effect of Hybrid Kernel and Iterative Reconstruction on Objective and Subjective Analysis of Lung Nodule Calcification in Low-Dose Chest CT.
10.3348/kjr.2018.19.5.888
- Author:
Seul Gi HONG
1
;
Eun Ju KANG
;
Jae Hyung PARK
;
Won Jin CHOI
;
Ki Nam LEE
;
Hee Jin KWON
;
Dong Ho HA
;
Dong Won KIM
;
Sang Hyeon KIM
;
Jeong Hyun JO
;
Jongmin LEE
Author Information
1. Department of Radiology, College of Medicine, Dong-A University, Busan 49201, Korea. medcarrot@dau.ac.kr
- Publication Type:Original Article
- Keywords:
Low-dose CT;
Iterative reconstruction;
Lung nodule;
Calcification
- MeSH:
Calcium;
Humans;
Lung*;
Research Design;
Thorax*;
Tomography, X-Ray Computed*
- From:Korean Journal of Radiology
2018;19(5):888-896
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the differences in subjective calcification detection rates and objective calcium volumes in lung nodules according to different reconstruction methods using hybrid kernel (FC13-H) and iterative reconstruction (IR). MATERIALS AND METHODS: Overall, 35 patients with small (< 4 mm) calcified pulmonary nodules on chest CT were included. Raw data were reconstructed using filtered back projection (FBP) or IR algorithm (AIDR-3D; Canon Medical Systems Corporation), with three types of reconstruction kernel: conventional lung kernel (FC55), FC13-H and conventional soft tissue kernel (FC13). The calcium volumes of pulmonary nodules were quantified using the modified Agatston scoring method. Two radiologists independently interpreted the role of each nodule calcification on the six types of reconstructed images (FC55/FBP, FC55/AIDR-3D, FC13-H/FBP, FC13-H/AIDR-3D, FC13/FBP, and FC13/AIDR-3D). RESULTS: Seventy-eight calcified nodules detected on FC55/FBP images were regarded as reference standards. The calcium detection rates of FC55/AIDR-3D, FC13-H/FBP, FC13-H/AIDR-3D, FC13/FBP, and FC13/AIDR-3D protocols were 80.7%, 15.4%, 6.4%, 52.6%, and 28.2%, respectively, and FC13-H/AIDR-3D showed the smallest calcium detection rate. The calcium volume varied significantly with reconstruction protocols and FC13/AIDR-3D showed the smallest calcium volume (0.04 ± 0.22 mm³), followed by FC13-H/AIDR-3D. CONCLUSION: Hybrid kernel and IR influence subjective detection and objective measurement of calcium in lung nodules, particularly when both techniques (FC13-H/AIDR-3D) are combined.
