The Impact of Skin Problems on the Quality of Life in Patients Treated with Anticancer Agents: A Cross-Sectional Study.
- Author:
Jaewon LEE
1
;
Jin LIM
;
Jong Seo PARK
;
Miso KIM
;
Tae Yong KIM
;
Tae Min KIM
;
Kyung Hun LEE
;
Bhumsuk KEAM
;
Sae Won HAN
;
Je Ho MUN
;
Kwang Hyun CHO
;
Seong Jin JO
Author Information
- Publication Type:Original Article
- Keywords: Adverse drug reaction; Antineoplastic agents; Quality of life; Dermatology Life Quality Index
- MeSH: Antineoplastic Agents*; Breast Neoplasms; Colorectal Neoplasms; Counseling; Cross-Sectional Studies*; Dermatology; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Inflammation; Medical Records; Pigmentation; Pruritus; Quality of Life*; Skin*
- From:Cancer Research and Treatment 2018;50(4):1186-1193
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: Patients treated with anticancer agents often experience a variety of treatment-related skin problems, which can impair their quality of life. MATERIALS AND METHODS: In this cross-sectional study, Dermatology Life Quality Index (DLQI) and clinical information were evaluated in patients under active anticancer treatment using a questionnaire survey and their medical records review. RESULTS: Of 375 evaluated subjects with anticancer therapy, 136 (36.27%) and 114 (30.40%) were treated for breast cancer and colorectal cancer, respectively. We found that women, breast cancer, targeted agent use, and longer duration of anticancer therapy were associated with higher dermatology-specific quality of life distraction. In addition, itching, dry skin, easy bruising, pigmentation, papulopustules on face, periungual inflammation, nail changes, and palmoplantar lesions were associated with significantly higher DLQI scores. Periungual inflammation and palmoplantar lesions scored the highest DLQI. CONCLUSION: We believe our findings can be helpful to clinicians in counseling and managing the patients undergoing anticancer therapy.
