Cytomegalovirus-Associated Severe Direct Antiglobulin Test Negative Hemolytic Anemia: A Case Report.
10.15264/cpho.2018.25.2.170
- Author:
Hyun Jung HONG
1
;
Young Hye CHO
;
Jae Young LIM
;
Jung Sook YEOM
;
Ji Sook PARK
;
Eun Sil PARK
;
Ji Hyun SEO
;
Hyang Ok WOO
;
Hee Shang YOUN
Author Information
1. Department of Pediatrics, College of Medicine, Gyeongsang National University, Korea. pedneu@gnu.ac.kr
- Publication Type:Case Report
- Keywords:
Hemolytic anemia;
Cytomegalovirus
- MeSH:
Anemia;
Anemia, Hemolytic*;
Child;
Coombs Test*;
Cytomegalovirus;
Cytomegalovirus Infections;
Diagnosis;
Diagnosis, Differential;
Female;
Hemolysis;
Humans;
Steroids
- From:Clinical Pediatric Hematology-Oncology
2018;25(2):170-174
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cytomegalovirus is a common virus that is mostly asymptomatic when infected, but rarely causes life-threatening hemolysis especially in immunocompromised children. We report a case of antiglobulin test negative severe hemolytic anemia caused by cytomegalovirus infection developed in an immune competent 9-year-old girl. The patient's hemoglobin level was 4.8 g/dL on the day of admission. The diagnosis was achieved by exclusion of other causes of hemolytic anemia and serological evidence of recent CMV infection. The patient was successfully treated with anti-viral agents and steroids resulting in recovery from anemia. Clinicians should consider cytomegalovirus infection in the differential diagnosis of hemolytic anemia in pediatric patients.
