The Imaging of Localization Related Symptomatic Epilepsies: The Value of Arterial Spin Labelling Based Magnetic Resonance Perfusion.
10.3348/kjr.2018.19.5.965
- Author:
Chinmay NAGESH
1
;
Savith KUMAR
;
Ramshekhar MENON
;
Bejoy THOMAS
;
Ashalatha RADHAKRISHNAN
;
Chandrasekharan KESAVADAS
Author Information
1. Department of Imaging Sciences & Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences & Technology (SCTIMST), Trivandrum 695011, India. kesav@sctimst.ac.in
- Publication Type:Case Report
- Keywords:
Epilepsy;
Seizures;
Neuroimaging;
Arterial spin labelling;
MR perfusion;
Non-contrast
- MeSH:
Electroencephalography;
Epilepsy*;
Magnetic Resonance Imaging;
Neuroimaging;
Neurovascular Coupling;
Perfusion*;
Seizures;
Status Epilepticus;
Tomography, Emission-Computed
- From:Korean Journal of Radiology
2018;19(5):965-977
- CountryRepublic of Korea
- Language:English
-
Abstract:
Accurate identification of the epileptogenic zone is an important prerequisite in presurgical evaluation of refractory epilepsy since it affects seizure-free outcomes. Apart from structural magnetic resonance imaging (sMRI), delineation has been traditionally done with electroencephalography and nuclear imaging modalities. Arterial spin labelling (ASL) sequence is a non-contrast magnetic resonance perfusion technique capable of providing similar information. Similar to single-photon emission computed tomography, its utility in epilepsy is based on alterations in perfusion linked to seizure activity by neurovascular coupling. In this article, we discuss complementary value that ASL can provide in the evaluation and characterization of some basic substrates underlying epilepsy. We also discuss the role that ASL may play in sMRI negative epilepsy and acute scenarios such as status epilepticus.
