Bleeding after Taking Dual Antiplatelets and NSAID Concurrently.
10.24304/kjcp.2018.28.3.250
- Author:
Jeongmin SEO
1
;
Joonghyuk CHOI
;
Pyoungwoo SON
;
Seungmin LEE
;
Hyunwoo CHAE
;
Geunhyung KANG
;
Eunhee JI
Author Information
1. College of Pharmacy, Gachon University, Incheon 21936, Republic of Korea. ehji@gachon.ac.kr
- Publication Type:Case Report
- Keywords:
Bleeding;
antiplatelet agents;
NSAIDs;
stenting;
osteoarthritis
- MeSH:
Aged;
Analgesics;
Anti-Inflammatory Agents, Non-Steroidal;
Aspirin;
Contusions;
Education;
Hemorrhage*;
Humans;
Middle Aged;
Myocardial Infarction;
Osteoarthritis;
Pharmacies;
Pharmacists;
Platelet Aggregation Inhibitors;
Prescriptions;
Stents;
Thrombosis;
Wrist
- From:Korean Journal of Clinical Pharmacy
2018;28(3):250-253
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
When stenting is applied to treat myocardial infarction, antiplatelet agents are administered to prevent thrombosis, which increases the risk of bleeding. Patients with myocardial infarction are also more likely to have osteoarthritis simultaneously, because both diseases occur frequently in elderly patients. Patients with osteoarthritis often use analgesics, especially nonsteroidal anti-inflammatory drugs (NSAIDs); hence, patients with both diseases use analgesics and antiplatelet agents simultaneously. The risk of bleeding increases with the use of antiplatelet agents and this is further increased when NSAIDs are added. We would like to report a case that reflects this situation. A 60-year-old man underwent stenting after ST-elevation myocardial infarction, and was treated with aspirin and clopidogrel. This patient also received a pelubiprofen prescription from another physician to treat osteoarthritis. After the patient took pelubiprofen twice, he found a bruise on his wrist and reported it to the pharmacist. It is unlikely that this is rare in community pharmacies, so pharmacists should pay careful attention to the concomitant administration of analgesics to patients receiving antiplatelet agents and should provide appropriate education to patients.
