Circumscribed Palmar Hypokeratosis Showing Bowenoid Change Secondary to Human Papilloma Virus.
- Author:
Woo Seok JEONG
1
;
Woo Jung JIN
;
Seung Hyun MOON
;
Hyun HWANGBO
;
Sook Kyung LEE
Author Information
1. Department of Dermatology, Maryknoll Medical Center, Busan, Korea. scholar04@naver.com
- Publication Type:Case Report
- Keywords:
Bowenoid epidermal change;
Circumscribed palmar hypokeratosis;
Cryotherapy;
Human papilloma virus;
Ingenol mebutate
- MeSH:
Cryotherapy;
Humans*;
Keratosis, Actinic;
Papillomaviridae*;
Skin
- From:Korean Journal of Dermatology
2018;56(8):489-493
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Circumscribed palmar or plantar hypokeratosis is a rare condition characterized by the occurrence of an erythematous, well-circumscribed, and depressed macule or patch on the palms or soles. Histopathologically, it is characterized by sharp, stair-like abrupt thinning of the horny layer between the affected and unaffected skin. The pathogenesis of this condition remains unclear. Recently, the human papilloma virus has been implicated as a possible etiological contributor. Circumscribed palmar or plantar hypokeratosis usually shows a benign course. Previous reports have not described malignant changes in these lesions. However, its association with actinic keratosis has been reported in a previous case. We report a case of circumscribed palmar hypokeratosis showing bowenoid epidermal change with expression of the human papilloma virus types 6 and 16 in a patient who was successfully treated with ingenol mebutate gel and cryotherapy.
