Basiliximab-Induced Non-Cardiogenic Pulmonary Edema in a Kidney Transplant Patient.
10.4285/jkstn.2018.32.3.63
- Author:
Yoo Jin LEE
1
;
Bong Soo PARK
;
Sihyung PARK
;
Kang Min PARK
;
Jin Han PARK
;
Il Hwan PARK
;
Yang Wook KIM
Author Information
1. Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. kyw8625@chol.com
- Publication Type:Case Report
- Keywords:
Basiliximab;
Pulmonary edema;
Kidney transplantation
- MeSH:
Anoxia;
Capillary Permeability;
Humans;
Kidney Transplantation;
Kidney*;
Korea;
Middle Aged;
Polycystic Kidney Diseases;
Pulmonary Edema*;
Shock
- From:The Journal of the Korean Society for Transplantation
2018;32(3):63-68
- CountryRepublic of Korea
- Language:English
-
Abstract:
Induction therapy with basiliximab is widely administered after kidney transplantation to prevent acute rejection. Herein, we report a case of non-cardiogenic pulmonary edema induced by basiliximab. To the best of our knowledge, such case has not been reported to date in Korea. A 54-year-old man with polycystic kidney disease received kidney transplantation. As induction therapy, he was prescribed basiliximab. On day 4, the second dose of basiliximab was administered. The patient complained of acute hypoxia 23 hours later, which led to circulatory collapse. He was discharged 3 weeks later with stable renal function. Pulmonary edema was presumed to have been caused by increased pulmonary capillary permeability. A possible hypothesis for this event occurring after the second basiliximab injection is steroid-related effects. Non-cardiogenic pulmonary edema is a complication that might occur after basiliximab induction therapy. Physicians should be aware of this potentially life-threatening complication.
