Postcholecystectomy syndrome: symptom clusters after laparoscopic cholecystectomy.
10.4174/astr.2018.95.3.135
- Author:
Hongbeom KIM
1
;
In Woong HAN
;
Jin Seok HEO
;
Min Gu OH
;
Chi Yeon LIM
;
Yoo Shin CHOI
;
Seung Eun LEE
Author Information
1. Department of Surgery, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
- Publication Type:Original Article
- Keywords:
Cholecystectomy;
Postcholecystectomy syndrome;
Quality of life
- MeSH:
Cholecystectomy;
Cholecystectomy, Laparoscopic*;
Consensus;
Constipation;
Diarrhea;
Gallbladder;
Postcholecystectomy Syndrome*;
Prospective Studies;
Quality of Life;
Risk Factors
- From:Annals of Surgical Treatment and Research
2018;95(3):135-140
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Postcholecystectomy syndrome (PCS) is characterized by abdominal symptoms following gallbladder removal. However, there is no consensus for the definition or treatment for PCS. The purpose of this study was to define PCS among various symptoms after laparoscopic cholecystectomy, and to identify risk factors affecting PCS. METHODS: This study was conducted at Dongguk University Ilsan Hospital and Chung-Ang University Hospital (2012–2013). Outcomes were assessed using European Organization for Research and Treatment of Cancer QLQ–C30 questionnaire. Symptom cluster for determining PCS was made by factor analysis. Cluster analysis evaluating risk factors of PCS was made by Ward methods and Dentogram. RESULTS: Factor analysis revealed three distinct symptom clusters, those are ‘insomnia and financial difficulties (eigenvalue, 1.707; Cronbach α, 0.190),’‘appetite loss and constipation (eigenvalue, 1.413; Cronbach α, 0.480),’ and ‘right upper quadrant (RUQ) pain and diarrhea (eigenvalue, 1.245; Cronbach α, 0.315).’ Among these symptom clusters, the cluster of ‘RUQ pain and diarrhea’ was determined as PCS. However, we could not find any risk factors between high symptomatic group and low symptomatic group. CONCLUSION: PCS could consist of RUQ pain and diarrhea. Well-designed prospective trials are needed to determine risk factors of PCS.