Long-term Survival after Repeated Local Therapy and Salvage Chemotherapy for Recurrent Metastases from Gastric Cancer: a Case Report and Literature Review.
- Author:
Jihyun KWON
1
;
Hye Sook HAN
;
Hee Kyung KIM
;
Seung Woo BAEK
;
Yaewon YANG
;
Ki Hyeong LEE
;
Seung Myoung SON
;
Won Dong KIM
;
Dae Hoon KIM
;
Hyo Yung YUN
Author Information
- Publication Type:Case Report
- Keywords: Chemotherapy; Gastric cancer; Metastasis; Radiotherapy; Surgery
- MeSH: Abdominal Wall; Adenocarcinoma; Aged; Drug Therapy*; Gastrectomy; Humans; Lymph Nodes; Male; Neoplasm Metastasis*; Radiotherapy; Stomach Neoplasms*
- From:Journal of Gastric Cancer 2018;18(3):305-312
- CountryRepublic of Korea
- Language:English
- Abstract: We report a rare case of long-term survival in a patient who received local therapy and salvage chemotherapy for recurrent metastases, along with a literature review. A 65-year-old male patient underwent subtotal gastrectomy for advanced gastric adenocarcinoma. Six months after gastrectomy, 2 metastatic intra-abdominal lymph node enlargements were detected, which were treated with radiotherapy. At 55 months after gastrectomy, an abdominal wall mass was detected, which was treated by surgical resection. The patient received 5-fluorouracil/leucovorin/irinotecan chemotherapy for 27 months before and after radiotherapy and docetaxel chemotherapy for 6 months after surgical resection of the abdominal wall metastasis. At the last visit, 7.8 years since the initial resection of the primary gastric cancer and 6.2 years since detection of the first metastases, the patient was disease-free and required no further chemotherapy. This case suggests that repeated local therapy offers potential for long-term survival in a carefully selected subset of patients with recurrent metastases.
