Dental Panoramic Radiographic Indices as a Predictor of Osteoporosis in Postmenopausal Saudi Women.
10.11005/jbm.2018.25.3.165
- Author:
Khaled Abdullah BALTO
1
;
Madiha Mahmoud GOMAA
;
Rabab Mohammed FETEIH
;
Najlaa Mohammed ALAMOUDI
;
Ayman Zaky ELSAMANOUDY
;
Mohammed Ahmed HASSANIEN
;
Mohammed Salleh M ARDAWI
Author Information
1. Center of Excellence for Osteoporosis Research, Faculty of Medicine, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia.
- Publication Type:Original Article
- Keywords:
Bone density;
Osteoporosis;
Postmenopause;
Radiography, panoramic;
Saudi Arabia
- MeSH:
Body Mass Index;
Bone Density;
Bone Diseases, Metabolic;
Calcium;
Collagen Type I;
Creatinine;
Diagnosis;
Estradiol;
Female;
Follicle Stimulating Hormone;
Humans;
Luteinizing Hormone;
Osteocalcin;
Osteoporosis*;
Postmenopause;
Radiography, Panoramic;
ROC Curve;
Saudi Arabia
- From:Journal of Bone Metabolism
2018;25(3):165-173
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Many oral presentations of osteoporosis-a bone metabolic disease-were recorded. Thus, we aimed to assess panoramic radiomorphometric indices with bone mineral density (BMD) values among Saudi postmenopausal women and its importance in the prediction of osteoporosis. METHODS: A total of 431 Saudi women were enrolled in this study. Panoramic radiographs were obtained at the time of BMD measurement. Subjects were fatherly classified into; normal BMD, osteopenia, and osteoporosis groups. Serum follicle-stimulating hormone, luteinizing hormone (LH), estradiol (E2), 25-hydroxy-vitamin D (25[OH]D) and intact-parathyroid hormone were measured. Moreover, serum creatinine, calcium, and phosphate, together with serum osteocalcin (s-OC), procollagen type I N-terminal propeptide (s-PINP) and cross-linked C-terminal telopeptide of type 1 collagen (s-CTX) were measured. Receiver-operator curve (ROC) curve analysis for use of mandibular cortical width (MCW), panoramic mandibular index (PMI), and maxillary-mandibular ratio (M/M ratio) to differentiate women with osteoporosis or osteopenia from normal subjects was calculated. Cut off values of 4.6 at T score <−1 and 4.1 at T score ≤−2.5 were used. RESULTS: Body mass index is significantly low in the osteoporotic group. There is no significant difference in serum levels of LH, E2, calcium, phosphate, and 25(OH)D between the studied groups. Moreover, s-OC, C-terminal propeptide of procollagen type I, s-PINP, s-CTX, and urinary-CTX are significantly higher in osteoporosis than normal and osteopenia groups. ROC curve analysis revealed that MCW and PMI showed significant data while M/M ratio is non-significant. CONCLUSIONS: It could be concluded that MCW as an important panoramic radiographic parameter can be used for prediction and diagnosis of osteoporosis in postmenopausal Saudi women with low BMD.
