Ventricular Arrhythmia during Tracheal Intubation and Extubation under General Anesthesia Possibly Induced by Amisulpride: A Case Report.
10.9758/cpn.2018.16.3.358
- Author:
Bo FANG
1
;
Hong MA
Author Information
1. Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang, China. drunk0630@126.com
- Publication Type:Case Report
- Keywords:
Amisulpride;
Ventricular arrhythmia;
Intubation;
intratracheal
- MeSH:
Anesthesia, General*;
Anti-Arrhythmia Agents;
Antipsychotic Agents;
Arrhythmias, Cardiac*;
Female;
Heart;
Humans;
Intubation*;
Schizophrenia
- From:Clinical Psychopharmacology and Neuroscience
2018;16(3):358-360
- CountryRepublic of Korea
- Language:English
-
Abstract:
We are presenting the first documented case of amisulpride related ventricular arrhythmia during tracheal intubation and extubation under general anesthesia in an 48 year-old female with psychiatric history of chronic schizophrenia who was treated with amisulpride. This case suggests the threshold of perioperative arrhythmia is possibly decreased in patients with long-term antipsychotic medication. So, the potential risk of antipsychotics-induced perioperative arrhythmia should be evaluated, as well as heart rhythm monitoring, prophylactic use of antiarrhythmic drugs, and preoperative adjustment of antipsychotics should be considered.