Mechanical properties and cytotoxicity of PLA/PCL films.
10.1007/s13534-018-0065-4
- Author:
Heeseok JEONG
1
;
Jeongwon RHO
;
Ji Yeon SHIN
;
Deuk Yong LEE
;
Taeseon HWANG
;
Kwang J KIM
Author Information
1. Convergence Institute of Biomedical Engineering and Biomaterials, Seoul National University of Science and Technology, Seoul 01811, Korea.
- Publication Type:Original Article
- Keywords:
Poly(lactic acid);
Poly(e-caprolactone);
Compatibilizer;
Tensile strength;
Cytotoxicity;
Cell proliferation
- MeSH:
Cell Proliferation;
Citric Acid;
Tensile Strength
- From:
Biomedical Engineering Letters
2018;8(3):267-272
- CountryRepublic of Korea
- Language:English
-
Abstract:
Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1–95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9 ± 3.5 MPa and the elongation at break of 10.3 ± 2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1 ± 3.4 MPa and the elongation at break of 8.8 ± 1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition.
