Inter-Vendor and Inter-Session Reliability of Diffusion Tensor Imaging: Implications for Multicenter Clinical Imaging Studies.
10.3348/kjr.2018.19.4.777
- Author:
Jeeyoung MIN
1
;
Mina PARK
;
Jin Woo CHOI
;
Geon Ho JAHNG
;
Won Jin MOON
Author Information
1. Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul 05030, Korea. mdmoonwj@kuh.ac.kr
- Publication Type:Multicenter Study ; Brief Communication
- Keywords:
Brain;
Diffusion tensor imaging;
Magnetic resonance;
Reliability;
Reproducibility
- MeSH:
Anisotropy;
Brain;
Commerce;
Diffusion Tensor Imaging*;
Diffusion*;
Female;
Healthy Volunteers;
Humans;
Male;
Prospective Studies
- From:Korean Journal of Radiology
2018;19(4):777-782
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the inter-vendor and inter-session reliability of diffusion tensor imaging (DTI) and relevant parameters. MATERIALS AND METHODS: This prospective study included 10 healthy subjects (5 women and 5 men; age range, 25–33 years). Each subject was scanned twice using 3T magnetic resonance scanners from three different vendors at two different sites. A voxel-wise statistical analysis of diffusion data was performed using Tract-Based Spatial Statistics. Fractional anisotropy (FA), mean diffusivity (MD), and radial diffusivity (RD) values were calculated for each brain voxel using FMRIB's Diffusion Toolbox. RESULTS: A repeated measures analysis of variance revealed that there were no significant differences in FA values across the vendors or between sessions; however, there were significant differences in MD values between the vendors (p = 0.020). Although there were no significant differences in inter-session MD and inter-session/inter-vendor RD values, a significant group × factor interaction revealed differences in MD and RD values between the 1st and 2nd sessions conducted by the vendors (p = 0.004 and 0.006, respectively). CONCLUSION: Although FA values exhibited good inter-vendor and inter-session reliability, MD and RD values did not show consistent results. Researchers using DTI should be aware of these limitations, especially when implementing DTI in multicenter studies.
