Predictors of One-Year Mortality in Smokers with Acute Myocardial Infarction.
10.3904/kjm.2018.93.4.369
- Author:
Soo Young SEOL
1
;
Myung Ho JEONG
;
Seung Hun LEE
;
Seok Joon SOHN
;
Min Chul KIM
;
Doo Sun SIM
;
Young Joon HONG
;
Ju Han KIM
;
Youngkeun AHN
;
Myeong Chan CHO
;
Chong Jin KIM
;
Young Jo KIM
Author Information
1. The Heart Center, Chonnam National University Hospital, Gwangju, Korea. myungho@chollian.net
- Publication Type:Original Article
- Keywords:
Smoking;
Myocardial infarction;
Mortality
- MeSH:
Academies and Institutes;
Angina Pectoris;
Creatine;
Follow-Up Studies;
Heart Failure;
Humans;
Hypertension;
Incidence;
Male;
Mortality*;
Multivariate Analysis;
Myocardial Infarction*;
Smoke;
Smoking;
Stroke Volume;
Ventricular Dysfunction, Left
- From:Korean Journal of Medicine
2018;93(4):369-378
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: It is well known that smoking is associated with clinical outcomes in patients with acute myocardial infarction (AMI). In this study, we aimed to predict the one-year mortality in AMI patients that smoked. METHODS: Of the AMI patients who were enrolled in the Korean Acute Myocardial Infarction Registry-National Institutes of Health study, 5,110 were current smokers (57.1 ± 11.6 years, male 95%), and these patients were included in the present study. Patients were divided into two groups; group I (survival group, n = 4,844, 56.5 ± 11.3 years, male 95%) and group II (deceased group, n = 266, male 88%). Clinical characteristics, coronary angiographic findings, procedural characteristics, and independent factors related to one-year mortality were analyzed. RESULTS: In group II, the incidence of hypertension and diabetes were significantly higher than in group I, and the patients were significantly older. Patients with history of angina pectoris, myocardial infarction, and heart failure were significantly more common in group II than in group I. Smoking duration and pack-years of smoking were also significantly longer in group II than in group I. Multivariate analysis revealed that creatine > 2 mg/dL, left ventricular ejection fraction < 40%, Killip class ≥ II, age ≥ 65 years, and post-percutaneous coronary intervention thrombolysis in myocardial infarction (post-PCI TIMI) flow ≤ II were independent factors of mortality during the one-year follow-up. CONCLUSIONS: The predictors of one-year mortality in AMI patients with smoking were renal and left ventricular dysfunction, high Killip class, old age, and low post-PCI TIMI flow.
