Chemotherapy Induced Peripheral Neuropathy, Sleep and Quality of Life among Patients with Gastric Cancer Receiving Chemotherapy.
10.7739/jkafn.2018.25.3.176
- Author:
Hyemi KIM
1
;
Hyojung PARK
Author Information
1. National Cancer Center · Graduate School of Clinical Health Sciences, Ewha Womans University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Chemotherapy adjuvant;
Stomach neoplasms;
Peripheral neuropathy;
Sleep;
Quality of life
- MeSH:
Ambulatory Care Facilities;
Drug Therapy*;
Humans;
Nursing;
Peripheral Nervous System Diseases*;
Quality of Life*;
Sleep Wake Disorders;
Stomach Neoplasms*
- From:Journal of Korean Academy of Fundamental Nursing
2018;25(3):176-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Purpose of this study was to investigate relationships and influence of peripheral neuropathy, sleep, and quality of life in patients with gastric cancer who are receiving chemotherapy. METHODS: Participants were 131 patients with gastric cancer being treated at a chemotherapy outpatient clinic and receiving chemotherapy. Data were analyzed using descriptive statistics, t-test, ANOVA, and multiple regression analysis with the SPSS program. RESULTS: Mean score for peripheral neuropathy was 24.66, for sleep, 6.71 and for quality of life, 67.69. Peripheral neuropathy had a significant positive correlation with sleep (r=.26, p=.003) and sleep had a significant negative correlation with quality of life (r=−.50, p < .001). The regression model explaining quality of patients' lives was significant (F=11.91, p < .001), peripheral neuropathy, sleep, and pain due to anticancer drugs and number ofneurotoxic anticancer drugs explained 25.1% of the variance in quality of life and sleep was the most important factor. CONCLUSION: To improve the quality of life for these patients, individualized nursing interventions for pain should be provided according to number of anticancer drugs in the chemotherapy. Also there is a need to identify ways to assess peripheral neuropathy and sleep disorders that are appropriate in the treatment and reduce side effects during treatment.
