An Experience of Various Pretransfusion Test Protocols in a Tertiary Referral Hospital.
10.17945/kjbt.2018.29.2.130
- Author:
Sooin CHOI
1
;
Sunghwan SHIN
;
Ji Young SEO
;
HongBi YU
;
Sejong CHUN
;
Duck CHO
Author Information
1. Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. duck.cho@skku.edu
- Publication Type:Original Article
- Keywords:
Pretransfusion test;
Emergency transfusion;
Universal blood;
Massive transfusion
- MeSH:
Blood Platelets;
Emergencies;
Erythrocytes;
Humans;
Korea;
Plasma;
Prescriptions;
Retrospective Studies;
Tertiary Care Centers*;
Tissue Donors;
Transfusion Reaction
- From:Korean Journal of Blood Transfusion
2018;29(2):130-139
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Pretransfusion tests are essential for safe transfusions, but occasionally, part or all can be omitted when a transfusion is needed urgently in an emergency. The purpose of this study was to share the authors' experience of various pretransfusion test protocols in a tertiary referral hospital in Korea. METHODS: From July 2016 to June 2017, all transfusion cases at Samsung Medical Center were analyzed retrospectively. For each pretransfusion test protocol, the parameters regarding issue, return and disposal rate of blood products, occurrence of hemolytic transfusion adverse effect, and prescription frequency of each respective department and ordering site were analyzed. RESULTS: A total of 90,539 units of red blood cells, 24,814 units of fresh frozen plasmas, 24,758 units of single donor platelets, and 23,303 units of platelet concentrates were issued during the study period. Among them, 3.6%, 1.8%, 0.3%, and 0.4% of red blood cells, fresh frozen plasmas, single donor platelets, and platelet concentrates were issued according to the emergency transfusion protocols. When various pretransfusion test protocols were applied to issue blood products, there was no case in which an adverse hemolytic transfusion reaction was suspected. When compared with usual pretransfusion test protocol, all emergency transfusion protocols showed significantly higher return and wastage rates in red blood cells and fresh frozen plasmas. Platelets also had a higher return and wastage rate, but the difference was not significant. CONCLUSION: These results suggests that there is no different risk of adverse hemolytic transfusion reaction regardless the pre-transfusion protocols, but management about of the increased rate of return and wastage of blood products in emergency transfusions should be considered.
