Clinical efficacy of transabdominal ultrasound-guided embryo transfer for in vitro fertilization and embryo transfer according to age of women.
- Author:
Dong Won KIM
1
;
Seok Hyun KIM
;
Eung Gi MIN
;
Seung Jae LEE
;
Jung Ryeol LEE
;
Young Sik CHOI
;
Byung Chul JEE
;
Seung Yup KU
;
Chang Suk SUH
;
Young Min CHOI
;
Jung Gu KIM
;
Shin Yong MOON
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Korea. seokhyun@snu.ac.kr
- Publication Type:In Vitro ; Original Article
- Keywords:
Ultrasound;
Embryo transfer;
IVF-ET;
Age
- MeSH:
Embryo Transfer*;
Embryonic Structures*;
Female;
Fertilization in Vitro*;
Gonadotropins;
Humans;
Oocytes;
Pregnancy;
Pregnancy Outcome;
Pregnancy Rate;
Ultrasonography
- From:Korean Journal of Obstetrics and Gynecology
2007;50(3):523-532
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To evaluate the clinical efficacy of transabdominal ultrasound-guided embryo transfer for in vitro fertilization and embryo transfer (IVF-ET) according to age of women. METHODS: A total of 211 cycles of IVF?ET were included in this study. The pregnancy outcomes were compared between transabdominal ultrasound?guided embryo transfer (USG-guided group, n=108) and clinical touch technique (Clinical touch group, n=103) groups. Then, comparative analysis was performed in women aged <35 years, 35~37 years and in those > or =38 years. RESULTS: Clinical characteristics of study subjects did not differ between the two groups. There was no difference between the two groups in terms of duration of controlled ovarian hyperstimulation, dose of gonadotropins used, numbers of oocytes retrieved and embryos transferred. Clinical pregnancy rate was significantly higher in USG-guided group than Clinical touch group (27.8% vs. 16.5%, p<0.05). This difference was also found in women 35~37 years (27.6% vs. 8.6%, p<0.05), but not in those <35 years. USG-guided group showed a significantly higher implantation rate in women 35~37 years (10.5% vs. 3.4%, p<0.05), but not in those <35 years. In women at 38 years or older, USG-guided group showed higher clinical pregnancy and implantation rates than Clinical touch group (15.0% vs. 7.6%; 4.8% vs. 2.5%, respectively), however the differences were not statistically significant. CONCLUSION: Transabdominal ultrasound-guided embryo transfer may improve the pregnancy outcomes in IVF-ET cycles, especially in women at age 35 years or older.
