Treatment-Resistant Schizophrenia : Pathophysiology and Treatment.
10.4306/jknpa.2018.57.3.230
- Author:
Euitae KIM
1
Author Information
1. Department of Psychiatry, College of Medicine, Seoul National University, Seoul, Korea. euitae.kim@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Treatment-resistant;
Schizophrenia;
Neurobiology;
Strategy
- MeSH:
Antipsychotic Agents;
Humans;
Neurobiology;
Schizophrenia*
- From:Journal of Korean Neuropsychiatric Association
2018;57(3):230-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A large proportion of patients with schizophrenia show a poor response to first-line antipsychotic drugs, which is termed treatment-resistant schizophrenia. Previous studies found that a different neurobiology might underlie treatment-resistant schizophrenia, which necessitates the development of different therapeutic approaches for treating treatment-resistant schizophrenia. This study reviewed previous studies on the pathophysiology of treatment-resistant schizophrenia and the pharmacological intervention, and forthcoming investigations of treatment-resistant schizophrenia are suggested.
