Tractional Retinal Detachment After Intravitreal Bevacizumab (Avastin(R)) Injection in Proliferative Diabetic Retinopathy.
10.3341/jkos.2009.50.11.1751
- Author:
Hyun Jai SONG
1
;
Hee Jin SOHN
;
Dae Yeong LEE
;
Dong Heun NAM
Author Information
1. Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea. eyedawns@gilhospital.com
- Publication Type:Case Report
- Keywords:
Bevacizumab;
Proliferative diabetic retinopathy;
Tractional retinal detachment
- MeSH:
Antibodies, Monoclonal, Humanized;
Diabetes Mellitus, Type 1;
Diabetic Retinopathy;
Eye;
Female;
Hemorrhage;
Humans;
Light Coagulation;
Macular Edema;
Membranes;
Middle Aged;
Porphyrins;
Retinal Detachment;
Retinaldehyde;
Traction;
Visual Acuity;
Vitrectomy;
Bevacizumab
- From:Journal of the Korean Ophthalmological Society
2009;50(11):1751-1754
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report two cases of tractional retinal detachment after intravitreal bevacizumab injection. CASE SUMMARY: (Case 1) A 48-year-old female with insulin-dependent diabetes mellitus and a high HbA1c level came to our clinic for fundus evaluation. The best corrected visual acuity (BCVA) was 1.0 in the right eye and funduscopic examination of the right eye revealed proliferative diabetic retinopathy with preretinal hemorrhage and a mild fibrovascular proliferative membrane around the optic disc. Intravitreal bevacizumab injection (1.25 mg) was performed before starting panretinal photocoagulation (PRP) to prevent macular edema after PRP. Three days after the injection, visual acuity decreased to 0.3 and funduscopic findings showed tractional retinal detachment. Vitrectomy was performed and visual acuity recovered to 1.0 four months after operation. CONCLUSIONS: Intravitreal bevacizumab injection may cause tractional retinal detachment in poorly controlled insulin-dependent diabetes mellitus patients with fibrovascular proliferative membranes.
