How Different Parts of the World Provide New Insights Into Food Allergy.
10.4168/aair.2018.10.4.290
- Author:
Elizabeth Huiwen THAM
1
;
Donald Y M LEUNG
Author Information
1. Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
- Publication Type:Review
- Keywords:
Food allergy;
genetics;
atopic dermatitis;
food allergy prevention
- MeSH:
Climate;
Dermatitis, Atopic;
Diagnosis;
Epidemiology;
Epigenomics;
Food Hypersensitivity*;
Genetics;
Humans;
Infant;
Polymorphism, Genetic;
Prevalence;
Primary Prevention
- From:Allergy, Asthma & Immunology Research
2018;10(4):290-299
- CountryRepublic of Korea
- Language:English
-
Abstract:
The prevalence and patterns of food allergy are highly variable in different parts of the world. Differences in food allergy epidemiology may be attributed to a complex interplay of genetic, epigenetic, and environmental factors, suggesting that mechanisms of food allergy may differ in various global populations. Genetic polymorphisms, migration, climate, and infant feeding practices all modulate food allergy risk, and possibly also the efficacy of interventions aimed at primary prevention of food allergy development. Approaches to diagnosis, treatment, and prevention of food allergy should thus be tailored carefully to each population's unique genetic and environmental make-up. Future research in the context of food allergy prevention should focus on elucidating factors determining differential responses between populations.
