Case of Raynaud Syndrome after the Use of Methimazole.
10.4078/jrd.2018.25.3.203
- Author:
Yunkyung KIM
1
;
Hee Sang TAG
;
Geun Tae KIM
;
Seung Geun LEE
;
Eun Kyung PARK
;
Ji Heh PARK
;
Seong min KWEON
;
Song I YANG
;
Jeong Hoon KIM
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea.
- Publication Type:Case Report
- Keywords:
Methimazole;
Raynaud syndrome;
Ulcer
- MeSH:
Connective Tissue Diseases;
Drug Therapy;
Extremities;
Female;
Humans;
Hyperthyroidism;
Hypesthesia;
Methimazole*;
Propylthiouracil;
Skin Pigmentation;
Smoke;
Smoking;
Ulcer
- From:Journal of Rheumatic Diseases
2018;25(3):203-206
- CountryRepublic of Korea
- Language:English
-
Abstract:
Raynaud syndrome is a medical condition that causes pain, numbness, and changes in skin color at the distal extremities. Raynaud syndrome can be subdivided into primary Raynaud's and secondary Raynaud's. The former is diagnosed when the cause is unknown and the latter is caused by an underlying condition, such as connective tissue diseases, injury, smoking, or certain medications. Both cancer chemotherapy and β-blockers are relatively common causes of Raynaud syndrome but there are no reports of its association with methimazole administration. The authors encountered a 43-year old woman with hyperthyroidism who developed digital ulcers associated with Raynaud syndrome after a methimazole treatment. Her digital ulcers and Raynaud syndrome were improved after methimazole was replaced with propylthiouracil and conventional therapy. This paper reports this case along with a review of the relevant literature.
