A 2-Week Steroid Trial for Differentiating Isolated IgG4-Related Sclerosing Cholangitis from Cholangiocarcinoma.
10.15279/kpba.2018.23.3.127
- Author:
Bho Hyeon LEE
1
;
Sung Hoon MOON
;
Kyueng Whan MIN
;
Ji Won PARK
;
Hyun LIM
;
Sung Eun KIM
;
Ho Suk KANG
;
Jong Hyeok KIM
Author Information
1. Department of Internal Medicine, Dongansan Hospital, Ansan, Korea.
- Publication Type:Case Report
- Keywords:
Immunoglobulin G4;
Sclerosing cholangitis;
Steroid;
Cholangiocarcinoma
- MeSH:
Aged;
Bile Ducts;
Cholangiocarcinoma*;
Cholangitis, Sclerosing*;
Female;
Humans;
Immunoglobulin G;
Immunoglobulins;
Klatskin Tumor;
Pancreatitis;
Rare Diseases
- From:Korean Journal of Pancreas and Biliary Tract
2018;23(3):127-133
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is rare disease which is steroid-responsive and often associated with IgG4 related systemic disease such as autoimmune pancreatitis. It is characterized by increased serum IgG4 and IgG4-positive lymphoplasmacytic infiltration in bile ducts. It is often difficult to distinguish IgG4-SC to hilar cholangiocarcinoma if it manifests as an isolated bile duct. We report a case of 79-year-old woman with IgG4-SC which was difficult to distinguish hilar cholangiocarcinoma due to similar clinical and radiologic findings, showing good therapeutic effect after a 2-week steroid trial.
