Neuroactivation studies using Functional Brain MRI.
- Author:
Gyung Ho CHUNG
1
Author Information
1. Department of Diagnostic Radiology, Chonbuk National University Medical School, Chonju, Chonbuk, Korea, Chonnam University Research Institute of Medical Sciences, Gwangju, Chonnam, Korea. chunggh@chonbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Magnetic resonance (MR);
functional image;
Magnetic resonance (MR);
functional study;
Brain;
cortex
- MeSH:
Brain*;
Echo-Planar Imaging;
Healthy Volunteers;
Humans;
Magnetic Resonance Imaging*;
Neurons;
Oxygen
- From:Korean Journal of Nuclear Medicine
2003;37(1):63-72
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Functional MRI (fMRI) provides an indirect mapping of cerebral activity, based on the detection of the local blood flow and oxygenation changes following neuronal activity (Blood Oxygenation Level Dependent). fMRI allows us to study noninvasively the normal and pathological aspects of functional cortical organization. Each fMRI study compares two different states of activity. Echo-Planar Imaging is the technique that makes it possible to study the whole brain at a rapid pace. Activation maps are calculated from a statistical analysis of the local signal changes. fMRI is now becoming an essential tool in the neurofunctional evaluation of normal volunteers and many neurological patients as well as the reference method to image normal or pathologic functional brain organization.
