Clinical Application of 2017 McDonald Diagnostic Criteria for Multiple Sclerosis.
10.3988/jcn.2018.14.3.387
- Author:
Vittorio MANTERO
1
;
Lucia ABATE
;
Roberto BALGERA
;
Loredana LA MANTIA
;
Andrea SALMAGGI
Author Information
1. Neurological Unit, MS Centre, A. Manzoni Hospital-ASST Lecco, Lecco, Italy. vittorio.mantero@hotmail.com
- Publication Type:Original Article
- Keywords:
multiple sclerosis;
clinically isolated syndrome;
criteria;
McDonald criteria;
oligoclonal bands
- MeSH:
Diagnosis;
Diagnostic Errors;
Humans;
Multiple Sclerosis*;
Oligoclonal Bands
- From:Journal of Clinical Neurology
2018;14(3):387-392
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND PURPOSE: McDonald criteria for multiple sclerosis diagnosis have been revised over the years, diagnostic procedures have been simplified and earlier diagnosis facilitated. The new 2017 revision introduces other important changes, with a further simplification for the diagnosis. Oligoclonal bands reassume a more relevant role in the workup. METHODS: We describe 3 typical cases of patients admitted for clinically isolated syndrome and illustrate how the application of the new criteria can change the diagnostic approach with respect to the previous criteria. RESULTS: In two of the three cases a diagnosis of multiple sclerosis is now possible. CONCLUSIONS: The new 2017 Multiple Sclerosis criteria may have an important impact in clinical practice with an earlier treatment to avoid the risk of disease dissemination. Their application requires a careful assessment to avoid misdiagnosis and mistreatments.
