Erectile dysfunction in diabetic nephropathy.
- Author:
Youn Kyoung LEE
1
;
Byoung Seok PARK
;
Taek Kyun JEONG
;
Gyun Ho JEONG
;
Seong Kwon MA
;
Soo Wan KIM
;
Nam Ho KIM
;
Ki Chun CHOI
Author Information
1. Department of Internal Medicin, Chonnam National University Medical School, Gwangju, Korea. Choikc@chonnam.chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Erectile dysfunction;
Diabetic nephropathy;
IIEF-5
- MeSH:
Coronary Disease;
Creatinine;
Diabetes Mellitus;
Diabetic Nephropathies*;
Diabetic Neuropathies;
Erectile Dysfunction*;
Foot;
Humans;
Jeollanam-do;
Logistic Models;
Male;
Prevalence;
Renal Replacement Therapy;
Risk Factors;
Smoke;
Smoking;
Triglycerides
- From:Korean Journal of Medicine
2003;64(2):188-196
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Erectile dysfunction (ED) is prevalent among patients with diabetes mellitus and impaired renal function. To estimate the prevalence of ED in diabetic nephropathy and to identify its risk factors, we carried out a survey of patients with diabetic nephropathy attending Chonnam University Hospital. METHODS: The presence of ED was assessed among 106 type 2 diabetic patients with microalbuminuria or overt diabetic nephropathy or renal replacement therapy using its self- administered International Index of Erectile Function (IIEF). ED was also classified into five validated severity levels, ranging from none (22-25), mild (17-21), mild/moderate (12-16), moderate (8-11), through severe (5-7). Logistic regression was used to examine associations between ED and other medical conditions. RESULTS: The mean age was 45.30+/-8.57 years in patients without ED and 58.53+/-8.46 years in patients with ED. The prevalence of any level of ED was 72% using IIEF. An independent t-test and chi-square demonstrated age, smoking, smoking duration, degree of nephropathy, coronary heart disease, neuropathy, diabetic foot, and retinopathy to be associated with the presence of any level of ED. Patients with ED had lower serum levels of hemoglobin, albumin, triglyceride, HDL-cholesterol and higher serum levels of BUN in unadjusted analyses compared with patients without ED. A multivariable logistic regression demonstrated age, serum creatinine concentration, and renal replacement therapy to be independently associated with the presence of any level of ED. CONCLUSION: ED is extremely prevalent among type 2 diabetic patients with microalbuminuria or overt diabetic nephropathy or renal replacement therapy. Increased age and serum creatinine concentration, and renal replacement therapy were associated with higher prevalence of ED.
