Gastritis Associated with Initially Pediatric Crohn's Disease and Ulcerative Colitis.
10.5223/pghn.2018.21.3.163
- Author:
Ahmet BASTURK
1
;
Reha ARTAN
;
Aygen YILMAZ
;
Mustafa T GELEN
Author Information
1. Department of Pediatric Gastroenterology, Faculty of Medicine, Akdeniz University, Antalya, Turkey. drahmetbasturk@hotmail.com
- Publication Type:Original Article
- Keywords:
Crohn's disease;
Child;
Gastritis;
Ulcerative colitis
- MeSH:
Child;
Colitis;
Colitis, Ulcerative*;
Colonoscopy;
Crohn Disease*;
Duodenitis;
Duodenum;
Endoscopy, Digestive System;
Esophagitis;
Esophagus;
Gastritis*;
Hand;
Humans;
Ulcer*
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2018;21(3):163-169
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study is to determine the involvement of the upper gastrointestinal system (GIS) in patients diagnosed with Crohn's disease (CD), ulcerative colitis (UC), and non-inflammatory bowel disease (IBD) and to compare their differences. METHODS: This study included patients aged between 2 and 18 years who underwent colonoscopy and esophagogastroduodenoscopy (EGD) for the first time due to the prediagnosis of IBD. In EGD, samples were taken from duodenum, antrum, corpus, and esophagus; and gastritis, duodenitis, and esophagitis were identified through histopathologic examination. The data gathered the ends of the research were compared between IBD with non-IBD groups and between CD-UC with non-IBD groups, and the presence of significant differences between groups were determined. RESULTS: In our study, 16 patients were diagnosed with CD, 13 with UC, 3 with undeterminate colitis, and 13 with non-IBD. In the histopathological examination of the groups, GIS involvement was found in 94.1% of patients diagnosed with IBD and in 38.5% of non-IBD patients. Moreover, the difference was found to be statistically significant (p=0.032). No significant difference was found between the CD and UC groups. Gastritis was mostly observed in 93.8% of CD-diagnosed patients, 76.8% of UC-diagnosed patients, 81.2% of IBD-diagnosed patients, and 38.5% of non-IBD-diagnosed patients. On the other hand, significant differences were found between CD and non-IBD groups (p=0.03), UC and non-IBD groups (p=0.047), and IBD and non-IBD groups (p=0.03). CONCLUSION: The results of the study show that gastritis was highly observed in UC- and CD-diagnosed patients than in non-IBD-diagnosed patients.
