A case of microscopic polyangiitis presenting with acute spinal subdural hemorrhage.
10.23876/j.krcp.2018.37.2.174
- Author:
Won Yong SUH
1
;
Eun Kyoung LEE
Author Information
1. Division of Nephrology, Department of Internal Medicine, Cheonan Medical Center, Cheonan, Korea.
- Publication Type:Case Report
- Keywords:
Microscopic polyangiitis;
Spinal;
Spinal subdural hematoma
- MeSH:
Autoantibodies;
Biopsy;
Decompression;
Female;
Glomerulonephritis;
Hematoma, Subdural*;
Hematoma, Subdural, Spinal;
Hemorrhage;
Humans;
Immunosuppression;
Microscopic Polyangiitis*;
Middle Aged;
Paraplegia;
Pathology;
Peroxidase;
Prognosis;
Vasculitis
- From:Kidney Research and Clinical Practice
2018;37(2):174-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
This report describes a case of a 62-year-old woman with microscopic polyangiitis (MPA) who developed acute spinal subdural hemorrhage. MPA was confirmed by positive autoantibodies to myeloperoxidase and focal segmental necrotizing and pauci-immune crescentic glomerulonephritis on renal biopsy. She did not recover from paraplegia due to acute spinal subdural hemorrhage, despite decompression operation and aggressive immunosuppression. Although spontaneous spinal hemorrhage in MPA patients is very rare, the prognosis for such patients is poor. Considering the possibility of ongoing vasculitis activity in extra-renal organs, clinicians should be very cautious to attenuate the strength of immunosuppressant drugs, even in patients with chronic or irreversible renal pathology.
