The Clinical Usefulness of Thermo-Sensitive Hydrogel-Type Allogeneic Keratinocytes for Treatment of Deep Second-Degree Burn.
- Author:
Dukju MOON
1
;
Banseok YANG
;
Jaejun SHIN
;
Jongho LEE
;
Sujeong PARK
;
Jungsun LEE
;
Suyeon LEE
Author Information
1. Department of Surgery, Bestian Seoul Hospital, Seoul, Korea. moondukju@hanmail.net
- Publication Type:Original Article
- Keywords:
Allogeneic keratinocyte;
Thermo-sensitive hydrogel;
Deep second degree burn
- MeSH:
Bandages;
Burns*;
Humans;
Keratinocytes*;
Marketing;
Re-Epithelialization
- From:Journal of Korean Burn Society
2018;21(1):6-11
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Aim of this study was to assess the safety and effectiveness of Keraheal-Allo® (Biosolution Co., Ltd., Korea) in patients with deep second-degree burn as a part of post marketing surveillance. METHODS: Seventy-five patients with deep second-degree burn were enrolled from April 2017 to October 2017. Keraheal-Allo, a thermos-sensitive hydrogel-type allogeneic keratinocytes, was applied to 90 deep second-degree burn sites of 75 patients. After application of Keraheal-Allo, the efficacy was assessed as the period of 100% re-epithelialization that was evaluated every time dressing was changed. RESULTS: The mean re-epithelialization period in the treated sites with KeraHeal-allo was 13.67±5.11 days. There was no severe adverse event. CONCLUSION: In conclusion, this thermo-sensitive hydrogel-type allogeneic keratinocytes have the clinical usefulness in terms of the safety, efficacy and ease of use.
