Surgical Options for Malignant Mesothelioma: A Single-Center Experience.
10.5090/kjtcs.2018.51.3.195
- Author:
Seung Ri KANG
1
;
Jin San BOK
;
Geun Dong LEE
;
Se Hoon CHOI
;
Hyeong Ryul KIM
;
Dong Kwan KIM
;
Seung Il PARK
;
Yong Hee KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea. kimyh67md@hotmail.com
- Publication Type:Original Article
- Keywords:
Malignant mesothelioma;
Pneumonectomy
- MeSH:
Cohort Studies;
Comorbidity;
Heart Failure;
Hospital Mortality;
Humans;
Length of Stay;
Male;
Mesothelioma*;
Mortality;
Pneumonectomy;
Pneumonia;
Recurrence;
Retrospective Studies;
Survival Rate
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2018;51(3):195-201
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We investigated the surgical outcomes of patients who underwent therapeutic surgery for malignant pleural mesothelioma (MPM) at a single center. METHODS: A retrospective review of 21 patients who underwent therapeutic surgery for MPM from January 2001 to June 2015 was conducted to assess their outcomes. The patients' characteristics and postoperative course, including complications, mortality, overall survival, and recurrence-free survival, were analyzed. RESULTS: Of the 21 patients who underwent therapeutic surgery, 15 (71.4%) underwent extrapleural pneumonectomy, 2 pleurectomy (9.5%), and 4 excision (19.1 %). The median age was 57 years (range, 32–79 years) and 15 were men (71.4%). The mean hospital stay was 16 days (range, 1–63 days). Median survival was 14.3 months. The survival rate was 54.2%, 35.6%, and 21.3% at 1, 3, and 5 years, respectively. In patients' postoperative course, heart failure was a major complication, occurring in 3 patients (14.3%). The in-hospital mortality rate was 2 of 21 (9.5%) due to a case of severe pneumonia and a case of acute heart failure. CONCLUSION: A fair 5-year survival rate of 21.3% was observed after surgical treatment. Heart failure was a major complication in our cohort. Various surgical methods can be utilized with MPM, each with its own benefits, taking into consideration the severity of the disease and the comorbidities of the patient. Patients with local recurrence may be candidates for surgical intervention, with possible satisfying results.
