Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement.
10.5090/kjtcs.2018.51.3.223
- Author:
Kanghoon LEE
1
;
Hyeong Ryul KIM
;
Jin ROH
;
You Jung OK
;
Bo Bae JEON
;
Young Woong KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Korea University Guro Hospital, Korea University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Erdheim-Chester disease;
Histiocytosis;
Non-Langerhans cell;
Mediastinum;
Video-assisted thoracic surgery
- MeSH:
Erdheim-Chester Disease*;
Histiocytes;
Histiocytosis;
Humans;
Mediastinum;
Middle Aged;
Sclerosis;
Thoracic Surgery, Video-Assisted
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2018;51(3):223-226
- CountryRepublic of Korea
- Language:English
-
Abstract:
Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred for evaluation of a mediastinal mass. The patient underwent surgical excision of the tumor via video-assisted thoracoscopic surgery. Histologic examination revealed marked proliferation of atypical histiocytes with sclerosis, and the results of immunohistochemical staining were suggestive of ECD.
