A Case of Packed red Cell Transfusion-Associated Anti-K Antibody.
- Author:
Bohyun KIM
1
Author Information
1. Department of Laboratory Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. bhkim@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Anti-K;
Transfusion;
Kell blood-group system;
Red cell alloantibodies
- MeSH:
Bacterial Infections;
Continental Population Groups;
Erythrocytes;
Humans;
Immunization;
Immunoglobulins;
Isoantibodies;
Kell Blood-Group System;
Phenotype;
Tissue Donors;
Transfusion Reaction
- From:Soonchunhyang Medical Science
2018;24(1):99-100
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anti-K alloantibody is a type of red blood cell (RBC) antibody which is generated through immunization. It is well noted that the anti-K antibody causes hemolytic transfusion reactions. Although Koreans generally do not have the K antigen on RBCs, we report a rare case of transfusion-related anti-K antibody in Korean patient. Just twelve pints of packed RBCs had been transfused to the patient before the anti-K was identified for the first time, but the donor information about Kell phenotype (K or k) was not available. The anti-K had been continuously detected, and the patient neither received immunoglobulins nor experienced bacterial infections which could generate anti-K antibody. Therefore we believe that her anti-K is the truly positive, previously transfused packed RBCs-related alloantibody. The packed RBCs transfused to our patient were likely to be donated from other races. The pre-transfusion irregular antibody detection test should be performed carefully to detect very rare RBC alloantibodies.
