Complications of Allograft Reconstruction following Wide Resection of Malignant Bone Tumors in Long Bones.
10.4055/jkoa.2018.53.3.264
- Author:
Kap Jung KIM
1
;
Sang Ki LEE
;
Chung Youb JEON
;
Chang Hyun MA
;
Su Min KIM
Author Information
1. Department of Orthopaedic Surgery, Eulji University College of Medicine, Daejeon, Korea. oskkj@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
malignant bone tumor;
wide resection;
allografts
- MeSH:
Adamantinoma;
Allografts*;
Diagnosis;
Female;
Femur;
Follow-Up Studies;
Fracture Fixation, Intramedullary;
Humans;
Humerus;
Inlays;
Male;
Multiple Myeloma;
Osteosarcoma;
Postoperative Complications;
Retrospective Studies;
Tibia;
Transplants
- From:The Journal of the Korean Orthopaedic Association
2018;53(3):264-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We evaluated the results of allograft reconstruction following wide resection of malignant bone tumors in long bone, retrospectively. MATERIALS AND METHODS: Seven patients were included. The mean age was 44 years old. Male was 4 cases, and female was 3 cases. Mean follow-up period was 38 months. The mean Musculoskeletal Tumor Society (MSTS) score at final follow-up was evaluated. Postoperative complications were evaluated via periodic radiologic follow-up. Oncologic results were analyzed at final follow-up. RESULTS: The primary malignancies occurred at femur in 5 cases, humerus in 1 case and tibia in 1 case. Pathologic diagnoses were osteosarcoma in 4 cases, multiple myeloma in 2 cases and adamantinoma in 1 case. Mean length of allograft was 165 mm. Fixations of allograft were intramedullary nailing with additional plate in 4 cases, intramedullary nailing in 2 cases, and screw fixation in 1 case. Mean time to union was 14.5 weeks. Mean MSTS score at final follow-up was 20 (67%). Postoperative complications were nonunion in 3 cases, implant failure in 1 case, and infection in 1 case. Oncologic outcomes were continuous disease free in 5 cases and alive with disease in 2 cases at final follow-up. Autologous bone graft and hemi-cortical onlay graft were performed in 2 cases of nonunion. CONCLUSION: Allograft reconstruction following wide resection of malignant bone tumors in long bone was effective surgical option. However, the possibility of nonunion between host bone and allograft should be considered.
