Bilateral Conjunctival Mucosa-Associated Lymphoid Tissue Type Lymphoma in a Kidney Transplant Recipient.
10.4285/jkstn.2018.32.2.26
- Author:
Eun Young JI
1
;
Ji Yeun CHANG
;
Chul Woo YANG
;
Seok Goo CHO
;
Byung Ha CHUNG
Author Information
1. Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. chungbh@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Kidney transplantation;
Marginal zone B-cell lymphoma;
Lymphoproliferative disorders
- MeSH:
Adult;
Diagnosis, Differential;
Herpesvirus 4, Human;
Humans;
Immunosuppression;
Kidney Transplantation;
Kidney*;
Lymphoid Tissue*;
Lymphoma*;
Lymphoma, B-Cell, Marginal Zone;
Lymphoproliferative Disorders;
Radiotherapy;
Sirolimus;
Tacrolimus;
Transplant Recipients*
- From:The Journal of the Korean Society for Transplantation
2018;32(2):26-30
- CountryRepublic of Korea
- Language:English
-
Abstract:
Lymphoproliferative disorder in a posttransplant setting has emerged as a difficult problem in kidney transplantation (KT). Lymphoma involving adnexa of the eye has rarely been reported due to scarcity of lymphoreticular tissue in the ocular area. This report presents a case of a 37-year-old KT recipient who was diagnosed with conjunctival mucosa-associated lymphoid tissue lymphoma with a chief complaint of seeing black spots. Unlike other post-transplant lymphoproliferative diseases associated with the Epstein-Barr virus (EBV) reactivation via immunosuppression, the lesion was not related to the virus. The patient received radiotherapy with concomitant conversion from the tacrolimus to the sirolimus. Overall, the results presented herein indicate lymphoma may be an important differential diagnosis when KT recipients complain of ocular discomfort.