Clinical features of eczema herpeticum in atopic dermatitis in a single center.
10.4168/aard.2018.6.3.174
- Author:
Hyun Ji JANG
1
;
Young Eun RHO
;
Kwanghoon KIM
;
Seong Heon KIM
;
Young Mi KIM
;
Hye Young KIM
Author Information
1. Department of Pediatrics, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. pearlhy@naver.com
- Publication Type:Original Article
- Keywords:
Atopic dermatitis;
Eczema herpeticum;
Herpes simplex virus;
Child;
Risk factor
- MeSH:
Blood Sedimentation;
Child;
Dermatitis, Atopic*;
Eczema*;
Eosinophils;
Food Hypersensitivity;
Head;
Humans;
Immunoglobulin E;
Impetigo;
Kaposi Varicelliform Eruption*;
Leukocyte Count;
Neck;
Prognosis;
Recurrence;
Retrospective Studies;
Risk Factors;
Simplexvirus;
Skin
- From:Allergy, Asthma & Respiratory Disease
2018;6(3):174-178
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study evaluated the clinical characteristics and risk factors associated with atopic dermatitis patients complicated by eczema herpeticum. METHODS: This study included 45 patients under the age of 18 with atopic dermatitis complicated by eczema herpeticum in the disease group (ADEH+), and 50 patients under the age of 18 with atopic dermatitis without any episode of eczema herpeticum in the control group (ADEH−). We retrospectively reviewed the clinical features, treatment and prognosis of the 2 groups. RESULTS: In this study, eczema herpeticum occurred in 2.7% of the AD patients. No significant difference in percentage of boys or mean age was found between the ADEH+ and ADEH− groups. In the ADEH+ group, eczema herpeticum occurred more frequently in the head and neck. Severe atopic dermatitis, recurrent impetigo, IgE−mediated atopic dermatitis and food allergy were identified as the risk factors of eczema herpeticum. The mean white blood cell count, erythrocyte sedimentation rate, percent of eosinophils and total serum IgE were higher in the ADEH+ group than in the ADEH− group. More than 2 recurrences were confirmed in 12 patients (26.7%). CONCLUSION: In the ADEH+ group, skin lesions were dominant on the head and neck. We revealed that severe atopic dermatitis, frequent impetigo, IgE-mediated atopic dermatitis, and food allergy are risk factors for eczema herpeticum.
