The Prevalence of Gallstone Disease Is Significantly Lower in Natives than in Migrants of Jeju Island.
10.4082/kjfm.2018.39.3.147
- Author:
Oh Sung KWON
1
;
Young Kyu KIM
;
Kyu Hee HER
Author Information
1. Interdisciplinary Postgraduate Program in Biomedical Engineering, Jeju National University, Jeju, Korea.
- Publication Type:Original Article
- Keywords:
Dietary Carbohydrates;
Alcohol Drinking;
Risk Factors;
Gallstones
- MeSH:
Alanine Transaminase;
Alcohol Drinking;
Blood Glucose;
Body Mass Index;
Cholesterol;
Diet;
Dietary Carbohydrates;
Eating;
Fasting;
Gallbladder;
Gallstones*;
Health Promotion;
Humans;
Korea;
Lipoproteins;
Liver Function Tests;
Logistic Models;
Medical Records;
Multivariate Analysis;
Population Groups*;
Prevalence*;
Risk Factors;
Transients and Migrants*;
Ultrasonography
- From:Korean Journal of Family Medicine
2018;39(3):147-154
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The eating habits of Jeju Island natives are quite different from those of the mainland people because of geographic isolation. Diet is a main factor affecting gallstone disease. We investigated the prevalence of gallstone disease in both Jeju Island natives and migrants and studied the risk factors affecting gallstone disease in the Jeju Island people. METHODS: A total of 20,763 subjects who underwent medical checkups at the Health Promotion Center of Jeju National University Hospital in Korea from January 2003 to December 2015 were enrolled in the study. Ultrasonography was used to determine the presence of gallbladder stones. Body mass index and biochemical parameters, including liver function test results, lipid profiles, and fasting blood glucose levels, were verified, and data on age, birthplace, and sex were collected from medical records. Univariate and multivariate analyses were performed to identify risk factors affecting gallstone disease. RESULTS: The prevalence of gallstone disease in the Jeju Island people was 4.0%: Jeju Island natives, 3.8% and migrants, 4.4% (P=0.047). After multivariate logistic regression analysis, the independent risk factors were older age, Jeju migrants, higher fasting blood glucose and alanine aminotransferase levels, and lower high-density lipoprotein cholesterol levels. CONCLUSION: The prevalence of gallstone disease was significantly lower in natives than in migrants from Jeju Island. Older age, Jeju migrants, higher fasting blood glucose and alanine aminotransferase levels, and lower high-density lipoprotein cholesterol levels contributed to gallstone disease prevalence in the Jeju Island people.
