Fundamental role of dendritic cells in inducing Th2 responses.
- Author:
Byoungjae KIM
1
;
Tae Hoon KIM
Author Information
- Publication Type:Review
- Keywords: Antigen-presenting cells; Dendritic cells; Th2 responses
- MeSH: Allergy and Immunology; Antigen-Presenting Cells; Dendritic Cells*; Immune System
- From:The Korean Journal of Internal Medicine 2018;33(3):483-489
- CountryRepublic of Korea
- Language:English
- Abstract: A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
