Acute Gastritis and Splenic Infarction Caused by Epstein-Barr Virus.
10.5223/pghn.2018.21.2.147
- Author:
Ji Eun JEONG
1
;
Kyung Moon KIM
;
Hye Lim JUNG
;
Jae Won SHIM
;
Deok Soo KIM
;
Jung Yeon SHIM
;
Moon Soo PARK
;
Soo Kyung PARK
Author Information
1. Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. hl.jung@samsung.com
- Publication Type:Case Report
- Keywords:
Herpesvirus 4;
human;
Gastritis;
Splenic infarction;
Infectious mononucleosis
- MeSH:
Adolescent;
Biopsy;
Child;
Endoscopy;
Endoscopy, Digestive System;
Epstein-Barr Virus Infections;
Fatigue;
Female;
Fever;
Gastritis*;
Herpesvirus 4, Human*;
Humans;
In Situ Hybridization;
Infectious Mononucleosis;
Lymphatic Diseases;
Pharyngitis;
Splenic Infarction*;
Splenic Rupture;
Stomach
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2018;21(2):147-153
- CountryRepublic of Korea
- Language:English
-
Abstract:
Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adolescents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture. We encountered a 16-year-old girl who presented with fever, fatigue, and epigastric pain. Splenic infarction and EBV-associated gastritis were diagnosed by using esophagogastroduodenoscopy and abdominal computed tomography. Endoscopy revealed a generalized hyperemic nodular lesion in the stomach, and the biopsy findings were chronic gastritis with erosion and positive in situ hybridization for EBV. As splenic infarction and acute gastritis are rare in infectious mononucleosis and are prone to be overlooked, we must consider these complications when an infectious mononucleosis patient presents with gastrointestinal symptom.
