Endoscopic Mucosal Resection for Premalignant Lesions and Early Gastric Cancer.
- Author:
Phil HO JUNG
1
;
Dong Ki LEE
;
Sang Cheol LEE
;
Jun Myeong KIM
;
Soon Koo BAIK
;
Il Hoi KIM
;
Yeun Jong CHOI
;
Do Yeun CHO
;
Chong IN LEE
;
Sang Ok KWON
Author Information
1. Department of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.
- Publication Type:Original Article
- Keywords:
Early gastric cancer;
Endoscopic mucosal resection(EMR);
Band ligation
- MeSH:
Adenoma;
Gastrectomy;
Hemorrhage;
Humans;
Ligation;
Lymph Nodes;
Mucous Membrane;
Prospective Studies;
SNARE Proteins;
Stomach;
Stomach Neoplasms*
- From:Korean Journal of Medicine
1998;54(4):494-501
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Gastrectomy with lymph node dissec tion is the standard treatment for early gastric can cer(EGC). However, patients who have high risks demand modifications in surgical treatment for EGC. Recently, endoscopic mucosal resection(EMR) has become accepted in many institutions as a treatment for cancerous mucosal lesions of the stomach. Thus we investigated the efficacy and safety of EMR prospectively in the patients with EGC who have high risks in surgery and those with premalignant lesions. METHOD: Twenty-five patients were treated with EMR, thirteen were EGC and twelve were premalignant lesions such as tubular adenoma, severe dysplasia. We used standard snare method and endoscopic mucosal resection using a band ligation kits(EMRL). RESULTS: The complete resection rate at the first step of EMR was 100%(12/12) in premalignant lesions, 76.9%(10/13) in EGC. Of three EGC resected incomple tely at the first step, one patient was treated by surgery and two patients underwent the third step of EMR. The final complete resection rate was 92%(23/25) and it was 100%(12/12) in the premalignant lesions, 84.6%(11/13) in EGC. The final complete resection rate in according to the methods was 100%(5/5) by standard snare method, 75%(6/8) by EMRL. As pathologic results, all cases of EGC were limited to the mucosa. No serious complications such as perforation, major bleeding were encountered. CONCLUSION: We consider that EMR is effective and safe in treatment of the patients with EGC who have high risks in surgery and those with premalignant lesions.
