A Case of Digoxin-like Immunoreactive Substance(DLIS) Poisoning After Ingestion of Fried Water Toad (Bufo Stejnegeri Schmidt).
- Author:
Hyun Cheol KWAK
1
;
Yong Leul OH
;
Han Jin KWON
;
Seong Joo OH
;
Soo Gil KIM
;
Kwang Seok KIM
;
Hae Jin YOO
;
Dong Jun WON
;
Jeong Sik PARK
Author Information
1. Department of internal medicine, Seoul Advantist Hospital Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Water toad;
Bufo stejnegeri Schmidt;
Digoxin-like immunoreactive substance;
Poisoning
- MeSH:
Bradycardia;
Digoxin;
Eating*;
Humans;
Immunoenzyme Techniques;
Male;
Middle Aged;
Poisoning*;
Vomiting
- From:Korean Journal of Medicine
1998;54(4):542-545
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Everybody knows that toads are not eatable because of their toxins. But water toads are very similar to frogs morphologically, so fried water toads are eaten by some people on occasion. It has been studied that the granular glands of the toads secrete toxins known as digoxin-like immunoreactive substances (DLIS) such as bufogenins and bufotoxins. DLIS have cross-reactivity with micro particle enzyme immunoassay for the quantitative mea surement of digoxin. We report a case of DLIS poisoning in 56-year-old male patient who showed vomiting, syn cope, and marked bradyarrhythmia with block (heart rate down to 29 beats per minute) after ingestion of the fried water toads (Bufo stejnegeri Schmidt).
