A Case of Diabetes Insipidus Following Tuberculous Meningitis.
- Author:
Sang Young KIM
1
;
Hyung Tae OH
;
Doek Suu LEE
;
Dong HO
;
Byung Yi ANN
;
Kwi Wan KIM
Author Information
1. Department of Internal Medicine, Presbyterian Medical Center, Cheon Ju, Korea.
- Publication Type:Case Report
- Keywords:
Tuberculous meningitis;
Diabetes Insipidus
- MeSH:
Adult;
Death, Sudden, Cardiac;
Diabetes Insipidus*;
Diabetes Insipidus, Nephrogenic;
Diabetes Insipidus, Neurogenic;
Head;
Humans;
Male;
Nervous System Diseases;
Osmolar Concentration;
Polydipsia, Psychogenic;
Polyuria;
Specific Gravity;
Tuberculosis, Meningeal*;
Vasopressins;
Water
- From:Korean Journal of Medicine
1998;54(4):568-571
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tuberculous menigitis is relatively common disease and delay in treatment is associated with many neurologic sequelae. Of the neurologic disorder, diabets insipidus is extreamly rare. Diabetes insipidus is a syndrome characterized by the excretion of abnormally large volumes of dilute urine. It is divided into central diabets insipidus, nephrogenic diabetes insipidus, primary polydipsia and gestational daibetes insipidus. In this four type of diabetes insipidus, central diabetes insipidus is a polyuric disorder results from a lack of sufficient antidiuretic hormone to effect appropriate concentration of the urine for water conservration. We report a 25-year old male who had prolonged head ache and subsequently followed by polyuria. He was dia gonsed as the tuberculous meningitis by laboratory find ing and smear of CSF, and diagnosed central diabetes insipidus by serum osmolality & Na+ & AVP (arginine va sopressin), urine osmolality & specific gravity, adminis tration of vasopressin. He maintained the water balance of body by administration of vasopressin, but without im provement of mental status, sudden cardiac arrest occurs on 20th hospital day
