Acute Hemolytic Transfusion Reaction due to ABO-Incompatible Blood Transfusion: A Fatal Case Report and Review of the Literature.
10.17945/kjbt.2018.29.1.73
- Author:
Hyeon Ho LIM
1
;
Kyeong Hee KIM
;
Gyu Dae AN
;
In Hwa JEONG
;
Young Ki SON
Author Information
1. Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea. progreen@dau.ac.kr
- Publication Type:Case Report
- Keywords:
ABO incompatible transfusion;
Hemolytic transfusion reaction;
Transfusion safety
- MeSH:
Acidosis, Lactic;
Aged;
Arthroplasty, Replacement, Knee;
Blood Transfusion*;
Colitis, Ischemic;
Disseminated Intravascular Coagulation;
Emergency Service, Hospital;
Erythrocytes;
Female;
Hemorrhage;
Humans;
Intensive Care Units;
Korea;
Patients' Rooms;
Pulmonary Edema;
Renal Replacement Therapy;
Transfusion Reaction*
- From:Korean Journal of Blood Transfusion
2018;29(1):73-78
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 77-year-old female patient who was suspected to have had an acute hemolytic transfusion reaction was admitted to the emergency room. She received one unit of type A red blood cells in a type B patient during a total knee arthroplasty operation at another medical institution. ABO-incompatible transfusion was carried out due to an identification error between the patient and blood product. At the time of admission, acute hemolytic reaction, lactic acidosis, and disseminated intravascular coagulation were observed. She was admitted to the intensive care unit and received continuous renal replacement therapy. She maintained renal function and was moved to the general ward on the 7th day. Complications such as pulmonary edema, gastrointestinal bleeding, and ischemic colitis persisted, and the patient died on the 111th after admission. This case is the first report of death due to an ABO-incompatible transfusion in Korea. Efforts to establish a safe transfusion environment are necessary not only at individual medical institutions but also at the national level.
