The Effectiveness of Light Emitting Diodes with 592 nm Yellow Light for Korean Photoaged Skin.
- Author:
Ki Rang MOON
1
;
Hyuck Hoon KWON
;
Dae Hun SUH
;
Sook Jung YUN
;
Seung Chul LEE
;
Jee Bum LEE
Author Information
1. Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. jbmlee@jnu.ac.kr
- Publication Type:Original Article
- Keywords:
Photoaged skin;
592 nm light emitting diode (LED);
Phototherapy
- MeSH:
Aging;
Cheek;
Collagen;
Elasticity;
Follow-Up Studies;
Humans;
Melanins;
Nasolabial Fold;
Phototherapy;
Pigmentation;
Rejuvenation;
Skin*
- From:Korean Journal of Dermatology
2015;53(9):677-683
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: As aging occurs, the skin develops more wrinkles and pigmentation, becomes drier, and loses its elasticity. In previous reports, light-emitting diode (LED) phototherapy was proven to stimulate collagen synthesis and accelerate fibroblast-myofibroblast transformation, which has a composite rejuvenation effect. OBJECTIVE: To evaluate the effectiveness and safety of LED phototherapy with 592 nm yellow light for photoaged skin. METHODS: Forty patients with photoaged skin (Korean photographic scale; grade 4approximately7) were enrolled and treated with an LED device producing 592+/-10 nm yellow light for 5 minutes twice a week for 4 weeks. The skin changes were assessed at 0, 2, 4, and 8 weeks by clinical photographs and the Cutometer(R) & Mexameter(R) (MPA 580, Courage+Khazaka Electronic GmbH, Koln, Germany). Measurements were made on the cheek, periorbital area, nasolabial fold, and glabella. RESULTS: At the final visit at 8 weeks, the Cutometer(R) parameters R4 and R6 decreased significantly compared to before treatment, from 0.118 to 0.099 for the periorbital (p=0.017) and 0.517 to 0.425 for the nasolabial fold (p=0.003). The average melanin index decreased significantly, from 133.65 to 124.55 (p<0.005). Fine improvement of wrinkles was shown grossly by reviewing follow-up clinical photographs. No adverse reactions occurred. LED phototherapy with 592+/-10 nm wavelength can be effective and safe in the treatment of photoaged skin. CONCLUSION: The findings suggest the LED with 592 nm yellow light might be an adjuvant therapeutic tool for photoaged skin.
