Establishing Reference Intervals for Complete Blood Cell Count in Healthy Korean Elderly Individuals.
10.15263/jlmqa.2018.40.1.27
- Author:
Eun Jin LEE
1
;
Miyoung KIM
;
Eunyup LEE
;
Kibum JEON
;
Jiwon LEE
;
Han Sung KIM
;
Hee Jung KANG
;
Young Kyung LEE
Author Information
1. Department of Laboratory Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea. rabbit790622@gmail.com
- Publication Type:Original Article
- Keywords:
Complete blood cell count;
Elderlies;
Reference interval
- MeSH:
Adult;
Aged*;
Blood Cell Count*;
Blood Cells*;
Blood Platelets;
Eosinophils;
Erythrocyte Indices;
Female;
Humans;
Male
- From:Journal of Laboratory Medicine and Quality Assurance
2018;40(1):27-37
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Different age groups may have different reference intervals. However, the currently used reference interval for complete blood count (CBC) in clinical laboratories is based on results from healthy adults between 20 and 50 years of age. In this study, we aimed to establish reference intervals for 16 CBC parameters in Korean healthy elderly individuals. METHODS: A total of 3,359 healthy adults were selected from 4,253 adults (aged ≥20 years) who underwent regular health check-ups, based on a medical examination by interview. The reference intervals for CBC in two groups (aged <60 and ≥60 years), and the partitioning of reference intervals between the two age groups were established. RESULTS: Most CBC parameters showed no significant differences in reference intervals between the two age groups. Among the men, platelet distribution width (PDW) was the only parameter that required a separate reference interval between the two age groups. Among the women, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), and eosinophil % required separate reference intervals between the two age groups. CONCLUSIONS: The reference intervals for most CBC parameters were not significantly different between the two age groups. Except for PDW in men and MCV, MCHC, RDW, and eosinophil % in women, reference intervals for CBC parameters in individuals younger than 60 years of age could also be applied to those that are 60 years of age or older.
