Association between vitamin D and urinary tract infection in children.
- Author:
Abolfazl MAHYAR
1
;
Parviz AYAZI
;
Sara SAFARI
;
Reza DALIRANI
;
Amir JAVADI
;
Shiva ESMAEILY
Author Information
- Publication Type:Original Article
- Keywords: 25-Hydroxyvitamin D; Urinary tract infection; Child
- MeSH: Case-Control Studies; Child*; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Urinary Tract Infections*; Urinary Tract*; Vitamin D*; Vitamins*
- From:Korean Journal of Pediatrics 2018;61(3):90-94
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: The present study aimed to determine the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and Urinary tract infections (UTIs) in children. METHODS: In this case-control study, 70 children with UTI (case group) were compared with 70 healthy children (control group) in terms of serum 25(OH)D levels. The children were between 1 month and 12 years of age. Serum 25(OH)D levels were measured using enzyme-linked immunosorbent assay (ELISA). The results were analyzed and compared between both groups. RESULTS: Among 70 children with UTI (case group), 5 children (7.2%) were male and 65 (92.8%) were female. Among the healthy children (control group), 9 (12.8%) and 61 children (87.2%) were male and female, respectively (P=0.39). The mean±standard deviation of age in the case and control groups were 53.2±35.6 and 36.1±60.2 months, respectively (P=0.24). The mean level of serum 25(OH)D in the case group was significantly higher than that of the control group (20.4±8.6 ng/mL vs. 16.9±7.4 ng/mL, P=0.01). CONCLUSION: This study showed that there was a relationship between serum 25(OH)D levels and UTI in children. It seems that 25(OH)D plays a role in the pathogenesis of UTI.
