Comparative Study of Esophageal Self-expandable Metallic Stent Insertion and Gastrostomy Feeding for Dysphagia Caused by Lung Cancer.
10.4166/kjg.2018.71.3.124
- Author:
Jihye KIM
1
;
Yang Won MIN
;
Hyuk LEE
;
Byung Hoon MIN
;
Joon Haeng LEE
;
Poong Lyul RHEE
;
Jae J KIM
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yangwon.min@samsung.com
- Publication Type:Comparative Study ; Original Article
- Keywords:
Self expandable metallic stents;
Gastrostomy;
Esophageal stenosis;
Lung cancer;
Dysphagia
- MeSH:
Deglutition Disorders*;
Esophageal Stenosis;
Gastrostomy*;
Hand;
Humans;
Lung Neoplasms*;
Lung*;
Malnutrition;
Multivariate Analysis;
Nutritional Status;
Quality of Life;
Retrospective Studies;
Self Expandable Metallic Stents;
Serum Albumin;
Stents*;
Survival Rate
- From:The Korean Journal of Gastroenterology
2018;71(3):124-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Dysphagia is encountered in a large proportion of patients with lung cancer and is associated with malnutrition and a poor quality of life. This study compared the clinical outcomes of self-expandable metallic stent (SEMS) insertion and percutaneous gastrostomy (PG) feeding for patients with lung cancer and dysphagia. METHODS: A total of 261 patients with lung cancer, who underwent either SEMS insertion (stent group) or PG (gastrostomy group) as an initial treatment procedure for dysphagia between July 1997 and July 2015 at the Samsung Medical Center, were reviewed retrospectively, and 84 patients with esophageal obstruction were identified. The clinical outcomes, including the overall survival, additional intervention, complications, and post-procedural nutritional status in the two groups, were compared. RESULTS: Among the 84 patients finally analyzed, 68 patients received SEMS insertion and 16 had PG. The stent group had less cervical obstruction and more mid-esophageal obstruction than the gastrostomy group. The Kaplan-Meier curves revealed similar overall survival in the two groups. Multivariate analysis showed that the two modalities had similar survival rates (PG compared with SEMS insertion, hazard ratio 0.682, p=0.219). Fifteen patients (22.1%) in the stent group received additional intervention, whereas there was no case in the gastrostomy group (p=0.063). The decrease in the serum albumin level after the procedure was lower in the gastrostomy group than in the stent group (-0.20±0.54 g/dL vs. -0.65±0.57 g/dL, p=0.013) CONCLUSIONS: SEMS insertion and PG feeding for relieving dysphagia by lung cancer had a comparable survival outcome. On the other hand, PG was associated with a better nutritional status.
