Longitudinal Melanonychia in Korean Patients: A Clinical and Histopathologic Study of 75 Cases.
- Author:
Su Hyun PARK
1
;
Ji Yeoun LEE
;
Tae Young YOON
Author Information
1. Department of Dermatology, School of Medicine and the Medical Research Institute, Chungbuk National University, Cheongju, Korea. tyyoon@chungbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Longitudinal melanonychia;
Melanonychia striata
- MeSH:
Biopsy;
Diagnosis;
Humans;
Medical Records;
Population Characteristics;
Skin;
Ulcer
- From:Korean Journal of Dermatology
2018;56(3):172-180
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Longitudinal melanonychia (LM) can be challenging as it may be caused by a wide variety of benign and malignant conditions. However, there are scarce data on LM confirmed by skin biopsy examination in Korean patients. OBJECTIVE: We sought to evaluate the clinical features and histopathologic diagnosis of LM in Korean patients. METHODS: We reviewed the medical records and clinical photographs of patients presenting with LM confirmed by skin biopsy examination between June 2007 and June 2017. RESULTS: Among a total of 75 patients with LM confirmed by skin biopsy examination at our hospital over a period of 10 years, 11 patients (14.7%) had malignant lesions. Common features of malignant lesions were involvement of a single nail, color heterogeneity, Hutchinson's sign, and nail plate dystrophy or ulceration. Common features of benign lesions were a negative Hutchinson's sign and absence of nail plate dystrophy and ulceration. CONCLUSION: This study analyzed the clinical features and histopathologic diagnosis of LM in Korean patients. Our data may contribute to determining the management approach for patients with LM.