Giant Vascular Eccrine Spiradenoma: Report of a Case with Immunohistochemical Study.
10.3346/jkms.2006.21.1.172
- Author:
Joo Youn KO
1
;
Chang Woo LEE
;
Sang Ho MOON
;
Kang Won SONG
;
Chan Kum PARK
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Giant Vascular Eccrine Spiradenoma;
Myoepithelial Cell;
Immunohistochemistry
- MeSH:
Actins/analysis;
Adenoma, Sweat Gland/blood supply/metabolism/*pathology;
Biological Markers/analysis;
CA-15-3 Antigen/analysis;
Eccrine Glands/blood supply/chemistry/*pathology;
Female;
Humans;
Immunohistochemistry;
Keratin/analysis;
Korea;
Membrane Proteins/analysis;
Middle Aged;
Muscle, Smooth/chemistry;
Sweat Gland Neoplasms/blood supply/metabolism/*pathology
- From:Journal of Korean Medical Science
2006;21(1):172-176
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a rare case of giant vascular eccrine spiradenoma (GVES) which developed in 56-yr-old Korean woman. It is a rare variant of eccrine spiradenoma (ES), which might be mistaken for angiomatous lesions in view of its florid vascularity and hemorrhagic features. Histogenesis of GVES is not clearly elucidated although it is known that ES presumably originates in the eccrine glands. To clarify the histogenesis of GVES, immunohistochemical stainings using various monoclonal antibodies were also performed. The tumor was composed of three types of cells, namely pale epithelial cells, small basal cells, and myoepithelial cells. Therefore, we conclude that GVES originated from eccrine gland and mainly differentiates toward secretory portion of secretory coil.
