Clinical Effects of High Flow Nasal Cannular Insufflation on Preoxygenation and Extension of Safe Apneic Period
- VernacularTitle:经鼻高流量吸氧对预充氧及安全窒息时限的影响
- Author:
Jun PENG
1
;
Yu-Qin CHEN
;
Jian-Hong YE
;
Xue-Ying YANG
;
Shu-Ling PENG
;
Zhi-Yi ZUO
Author Information
1. 中山大学孙逸仙纪念医院麻醉科
- Keywords:
high flow nasal cannular insufflation;
preoxygenation;
safe apneic period
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2018;39(2):263-268
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To assess the effects of high flow nasal cannular insufflation(HFNCI)on preoxygenation and extension of safe apneic period during tracheal intubation.[Methods]Patients were randomly allocated into facemask(FM),facemask plus HFNCI(FM+HFNCI),HFNCI and HFNCI plus nasopharyngeal airway(HFNCI+NPA) groups. Facemask was adopted in FM and FM+HFNCI groups,while HFNCI was used in HFNCI and HFNCI+NPA groups for preoxygenation. All patients except for those in FM group received HFNCI during tracheal intubation. PaO2, SaO2,HR and MAP were recorded and analyzed.[Results]There was no significant difference in PaO2and SaO2after preoxygenation among groups(P>0.05). During apneic tracheal intubation period,PaO2decreased significantly in FM group while increased in HFNCI+NPA group. The Δ PaO2in FM group(Mean value was -5.4 kPa)was significantly bigger than those in other groups(Mean values in FM+HFNCI,HFNCI,and HFNCI+NPA groups were -0.5,-0.8 and 1.4 kPa,respectively(P < 0.001). All values at the success of tracheal intubation were much above the safe limits.[Conclusion]HFNCI provides effective preoxygenation and may extend safe apneic period in patients with patent airway.
