Influence of the Single Live Birth Outcome Following Transfer of Vitrified Blastocyst and Blastocyst Cultured from Thawing Cleavage Embryo
- VernacularTitle:玻璃化对复苏囊胚移植单胎分娩结局的影响
- Author:
Han-Yan LIU
1
;
Shi-Ping CHEN
;
Hong-Zi DU
;
Li LI
;
Rui CHEN
Author Information
1. 广州医科大学附属第三医院生殖医学中心//广东省生殖医学重点实验室//广东省产科重大疾病重点实验室//广东省普通高校生殖与遗传重点实验室
- Keywords:
vitrification;
cleavage stage;
blastocyst culture;
blastocyst transfer;
single live birth outcomes
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2018;39(2):238-244
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To compare the single live birth outcomes of blastocyst transfer between vitrified blastocyst and blastocyst cultured from thawing cleavage embryo,so as to choose the best scheme of blastocyst transfer.[Methods]Retrospective analysis of the single live birth clinical data of 1 037 vitrified blastocyst compared with 690 blastocyst cul-tured from thawing cleavage embryo undergoing frozen embryo transplantation(FET)from January 2014 to October 2016 was performed.Mail outcome were including gestational age,neonatal weight,proportion of male neonate,preterm birth rate,very preterm birth rate,low birthweight rate,very low birthweight rate,congenital anomalies rate.[Results]There were no differences between the two groups for gestational age,neonatal weight,proportion of Live birth,health baby and stillbirth(P>0.05). There were no differences in proportion of male neonate(AOR 1.07,95% CI 0.86~1.34),preterm birth rate(AOR 0.7,95% CI 0.49~1.01),very preterm birth rate(AOR 1.47,95% CI 0.55~3.96),low birthweight rate (AOR 1.38,95% CI 0.86~2.22),very low birthweight rate(AOR 0.76,95% CI 0.20~2.83),congenital anomalies rate (AOR 1.58,95% CI 0.66~3.76,P>0.05).[Conclusion]The blastocyst may be the preferable stage for vitrifying and transfer currently which can obtain good neonatal outcomes.